Palliative

WHY PALLIATIVE CRYO?

PALLIATIVE INTERVENTION

Significant decrease in pain for patients with metastatic disease. (7)
Able to treat large zones and geometrically difficult tumors in one treatment. (7)
Effective treatment for osteolytic metastatic focal pain. (7)

Benefits of PerCryo Treatment

HIGHLY VISIBLE UNDER IMAGE GUIDANCE

CT imaging produces a 40 Hounsfield unit drop in attenuation. (8)
CT allows for complete visual monitoring and verification of the ice ablation zone.

DECREASED PAIN DURING & POST PROCEDURE

Ice formation produces a natural pain anesthetic. (9)
Clinical studies have shown reduced narcotics during and post procedures. (9)

DOES NOT DESTROY COLLAGEN

Ice allows the natural tissue architecture to remain intact.
Treatments are possible near and around critical vessels and structures. (1)

ICE PROPAGATION IS PREDICTABLE & REPRODUCIBLE

Reproducible and predictable ice propagation provides enhanced control.
Consistent ice formation provides simple and accurate planning and monitoring.

MULTIPLE CRYOPROBES MAY BE USED SIMULTANEOUSLY

Multiple Cryoprobes used simultaneously can create a large ablation zone.
Multiple Cryoprobes allow treatment of multiple tumors concurrently.

1) Sung GT, Gill IS, Hsu THS, et al: Effect of intentional cryo-injury to the renal collecting system. J Urol 170: 619-622, 2003.

7) Callstrom MR, Atwell TD, Charboneu JW, et al. Painful Metastases Involving Bone: Percutaneous Image-guided Cryoablation – Prospective Trial Interim Analysis. Radiology 241: 572-580, 2006.

8) Sandison GA, et al: X-ray CT Monitoring of Iceball Growth and Thermal Distribution During Cryosurgery. Phys Med Biol 43: 3309-3324, 1998.

9) Allaf ME, Varkarakis I, Bhayani SB, et al. Pain Control Requirements for Percutaneous Ablation of Renal Tumors: Cryoablation versus Radiofrequency Ablation – Initial Observations. Radiology 237: 366-370, 2005.

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